![]() Department of Molecular Biology and Biotechnology. Food Microbiol 20:489–493Īish JL (2003) Environmental regulation of virulence determinant expression in Staphylococcus aureus. Int J Food Microbiol 65:173–182Īcco M, Ferreira FS, Henriques JAP, Tondo EC (2003) Identification of multiple strains of Staphylococcus aureus colonizing nasal mucosa of food handlers. Understanding the molecular mechanisms that govern desiccation tolerance may determine the break points to be exploited to prevent the spread of this dangerous pathogen in hospitals and communities.Ībadias M, Benabarre A, Teixidó N, Usall J, Viñas I (2001) Effect of freeze-drying and protectants on viability of the biocontrol yeast Candida sake. SigB is an accessory sigma factor with a role in generalized stress resistance. ClpX is a part of the ATP-dependent ClpXP protease, important for protein turnover, and YjbH has a proposed linked function. Using a combination of a random screen and defined mutants, clpX, sigB and yjbH were identified as being required for desiccation tolerance. aureus has the ability to survive on dry plastic surfaces for more than 1,097 days. ![]() This established a robust model of desiccation tolerance in which S. Initially, the role of environmental parameters such as temperature, growth phase, cell density, desiccation time and protectants in desiccation tolerance were determined. aureus and identified several components involved in the process. ![]() This study investigated parameters governing desiccation tolerance of S. Staphylococcus aureus is a multidrug-resistant pathogen that not only causes a diverse array of human diseases, but also is able to survive in potentially dry and stressful environments, such as the human nose, on skin and on inanimate surfaces such as clothing and surfaces.
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